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Outcomes

What does ibogaine change — and does it last?

51 papers

2020s · 24

Geoly et al.Increased cortical thickness and decreased brain age among special operations veterans with blast TBI after a magnesium-ibogaine protocol
iScience·2026·Cohort
Carlucci et al.Ibogaine microdosing in a patient with bipolar depression: case report
Archives of Health·2025·Case report
Chen et al.Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis
Frontiers in Immunology·2025·Case report
Erny et al.Ibogaine for the treatment of Parkinson's disease: A case report
Journal of Psychedelic Studies·2025·Case report
Faerman et al.Is ibogaine treatment durable? 12-month follow-up of magnesium-ibogaine therapy (MISTIC) in Special Operations Veterans with traumatic brain injuries
Preprint·2025·Cohort
Gomes et al.Ibogaine as a Tool in the Process of Overcoming Drug Addiction
Brill·2025·Review
Lissemore et al.Magnesium–ibogaine therapy effects on cortical oscillations and neural complexity in veterans with traumatic brain injury
Nature Mental Health·2025·Cohort
Rocha et al.Tolerabilidade e eficácia da ibogaína no tratamento do transtorno por uso de álcool: um estudo aberto e de escalonamento de doses
2025·Cohort·withdrawn
StaveleyExploring Ibogaine/5-MeO-DMT as Treatment for the Relief of PTSD Symptoms in Veterans
2025·Qualitative
Swieczkowski et al.Not Losing Momentum: Cross-Sectional Insights into Ibogaine Clinical Trials
Journal of Psychoactive Drugs·2025·Syst. review
Cherian et al.Magnesium–ibogaine therapy in veterans with traumatic brain injuries
Nature Medicine·2024·Cohort
Oña EsteveIbogaine for the Treatment of Opioid Dependence: From Mechanisms of Action to Clinical Efficacy
Universitat Rovira i Virgili (PhD Thesis)·2024·Review
Cherian et al.The Effect of Ibogaine on Cognitive Functioning
Journal of the International Neuropsychological Society·2023·Cohort
Davis et al.Open-label study of consecutive ibogaine and 5-MeO-DMT assisted-therapy for trauma-exposed male Special Operations Forces Veterans: prospective data from a clinical program in Mexico
American Journal of Drug and Alcohol Abuse·2023·Observational
Dickinson et al.Ibogaine reduced severe neuropathic pain associated with a case of brachial plexus nerve root avulsion
Frontiers in Pain Research·2023·Case report
Faerman et al.Ibogaine Treatment in Combat Veterans Significantly Improves Sleep, Beyond Alleviating Posttraumatic Stress Disorder Symptoms
SLEEP·2023·Cohort
Kratina et al.Tripping Outside the Lines: Lessons from Observational Studies of Combination Psychedelic Use Beyond Regulated Clinical Contexts
American Journal of Drug and Alcohol Abuse·2023·Review
Mosca et al.Ibogaine/Noribogaine in the Treatment of Substance Use Disorders: A Systematic Review of the Current Literature
Current Neuropharmacology·2023·Syst. review
Fernandes-Nascimento et al.Ibogaine microdosing in a patient with bipolar depression: a case report
Brazilian Journal of Psychiatry·2022·Case report
Köck et al.A Systematic Literature Review of Clinical Trials and Therapeutic Applications of Ibogaine
Journal of Substance Abuse Treatment·2022·Syst. review
Underwood et al.A narrative review of the pharmacological, cultural and psychological literature on ibogaine
Journal of Psychedelic Studies·2021·Review
CanessaIbogaine and Noribogaine in the Treatment of Drug Dependency: A State of the Art Review about Safety and Efficacy
2020·Syst. review
Davis et al.Psychedelic Treatment for Trauma-Related Psychological and Cognitive Impairment Among US Special Operations Forces Veterans
Chronic Stress·2020·Observational
Wilson et al.Novel treatment of opioid use disorder using ibogaine and iboga in two adults
Journal of Psychoactive Drugs·2020·Case report

2010s · 16

Barsuglia et al.A case report SPECT study and theoretical rationale for the sequential administration of ibogaine and 5-MeO-DMT in the treatment of alcohol use disorder
Progress in Brain Research·2018·Case report
Brown et al.Treatment of Opioid Use Disorder with Ibogaine: Detoxification and Drug Use Outcomes
The American Journal of Drug and Alcohol Abuse·2018·Observational
Davis et al.A Mixed-Method Analysis of Persisting Effects Associated with Positive Outcomes Following Ibogaine Detoxification
Journal of Psychoactive Drugs·2018·Observational
Knuijver et al.Hallucinogen Persisting Perception Disorder After Ibogaine Treatment for Opioid Dependence
Journal of Clinical Psychopharmacology·2018·Case report
Malcolm et al.Changes in Withdrawal and Craving Scores in Participants Undergoing Opioid Detoxification Utilizing Ibogaine
Journal of Psychoactive Drugs·2018·Observational
Mash et al.Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes
Frontiers in Pharmacology·2018·Observational
Davis et al.Subjective effectiveness of ibogaine treatment for problematic opioid consumption: Short- and long-term outcomes and current psychological functioning
Journal of Psychedelic Studies·2017·Observational
dos Santos et al.The antiaddictive effects of ibogaine: A systematic literature review of human studies
Journal of Psychedelic Studies·2017·Syst. review
Noller et al.Ibogaine treatment outcomes for opioid dependence from a twelve-month follow-up observational study
The American Journal of Drug and Alcohol Abuse·2017·Observational
Belgers et al.Ibogaine and addiction in the animal model, a systematic review and meta-analysis
Translational Psychiatry·2016·Syst. review
Cloutier-Gill et al.Remission of Severe Opioid Use Disorder with Ibogaine: A Case Report
Journal of Psychoactive Drugs·2016·Case report
Forsyth et al.Effects of low dose ibogaine on subjective mood state and psychological performance
Journal of Ethnopharmacology·2016·RCT
Prior et al.Ibogaine Effect on Cocaine Craving and Use in Dependent Patients - A Double-Blind, Placebo-Controlled Pilot Study
Jacobs Journal of Addiction and Therapy·2014·RCT
Schenberg et al.Treating drug dependence with the aid of ibogaine: A retrospective study
Journal of Psychopharmacology·2014·Observational
BrownIbogaine in the Treatment of Substance Dependence
Current Drug Abuse Reviews·2013·Review
Houenou et al.Ibogaine-Associated Psychosis in Schizophrenia: A Case Report
Journal of Clinical Psychopharmacology·2011·Case report

2000s · 5

Alper et al.The Use of Ibogaine in the Treatment of Addictions
2007·Review
Hittner et al.Combating Substance Abuse with Ibogaine: Pre- and Posttreatment Recommendations and an Example of Successive Model Fitting Analyses
Journal of Psychoactive Drugs·2004·Review
Lotsof et al.Case Studies of Ibogaine Treatment: Implications for Patient Management Strategies
The Alkaloids: Chemistry and Biology·2001·Case series
Alper et al.Ibogaine in Acute Opioid Withdrawal: An Open Label Case Series
Annals of the New York Academy of Sciences·2000·Case series
Luciano et al.Neurologic, Electroencephalographic and General Medical Observations in Subjects Administered Ibogaine
MAPS Bulletin·2000·Case series

1990s · 6

Alper et al.Treatment of Acute Opioid Withdrawal with Ibogaine
American Journal on Addictions·1999·Case series
Rezvani et al.Attenuation of Alcohol Intake by Ibogaine in Three Strains of Alcohol-Preferring Rats
Pharmacology Biochemistry and Behavior·1995·Preclinical
De Rienzo et al.The Ibogaine Story — Chapter 6: Bob Sisko
1995·Qualitative
SheppardA Preliminary Investigation of Ibogaine: Case Reports and Recommendations for Further Study
Journal of Substance Abuse Treatment·1994·Case series
Cappendijk et al.Inhibitory effects of ibogaine on cocaine self-administration in rats
European Journal of Pharmacology·1993·Preclinical
Glick et al.Effects and aftereffects of ibogaine on morphine self-administration in rats
European Journal of Pharmacology·1991·Preclinical