The Use of Ibogaine in the Treatment of Addictions
Outcomes Review high
⚠ Contains fatality data
AI-extracted · unverified · confirm at source
Comprehensive Alper–Lotsof review: 65 patients across two case series showing opioid withdrawal resolution within 24h, dosing protocols (10–25 mg/kg oral), pharmacology, mechanisms, and the global treatment landscape as of 2007.
Dosing: 10–25 mg/kg oral (single dose); boosters at half-dose; low-dose regimens 25–50 mg/day (oral)
Contraindications: Pre-existing cardiovascular disease, Cardiac arrhythmia history, Prior endocarditis (especially intravenous drug users), Concurrent drug use during treatment