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A Preliminary Investigation of Ibogaine: Case Reports and Recommendations for Further Study

Sheppard, Simon G. · 1994 · Journal of Substance Abuse Treatment

Outcomes Case series landmark

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First published case series (N=7): ibogaine 700–1800 mg (11.7–25 mg/kg) abolished opiate withdrawal in all subjects; 3/7 remained drug-free ≥14 weeks; higher doses correlated with better outcomes.

Dosing: 700–1,800 mg ibogaine hydrochloride (11.7–25 mg/kg); 100–200 mg trial dose followed by remainder (oral)

Sample size: 7

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