Open-label study of consecutive ibogaine and 5-MeO-DMT assisted-therapy for trauma-exposed male Special Operations Forces Veterans: prospective data from a clinical program in Mexico

Davis, Alan Kooi, Xin, Yitong, Sepeda, Nathan, Averill, Lynnette A. · 2023 · American Journal of Drug and Alcohol Abuse

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SOFV prospective n=86: Ibogaine 10mg/kg + 5-MeO-DMT 50mg over 3 days. Large improvements in PTSD (η²=0.414), depression, anxiety, insomnia, post-concussive symptoms at 1-month. Effects sustained to 6-months.

Dosing: 10 mg/kg ibogaine HCl + 5-MeO-DMT 50mg total (oral)

Sample size: 86

Contraindications: Cardiac abnormalities on ECG screening, Contraindicated medications without proper taper