The antiaddictive effects of ibogaine: A systematic literature review of human studies
Outcomes Syst. review moderate
AI-extracted · unverified · confirm at source
Systematic review of 8 human studies: 7 open-label case series suggest single ibogaine dose reduces opioid withdrawal within 24h lasting weeks-months; 1 noribogaine RCT (n=27) found no significant effect.
Safety data present: QTC
Contraindications: Pre-existing cardiovascular disease, Concomitant opiate/opioid use during or immediately after ibogaine, Use of drugs of unknown purity in uncontrolled settings