Treatment of Acute Opioid Withdrawal with Ibogaine

Alper, Kenneth R., Lotsof, Howard S., Frenken, Geerte M. N., Luciano, Daniel J., Bastiaans, Jan · 1999 · American Journal on Addictions

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Landmark case series: n=33 opioid-dependent patients (avg 0.64 g heroin/day IV). 76% (25/33) achieved complete withdrawal resolution within 24h sustained 72h. One fatality (possible surreptitious heroin use).

Dosing: 19.3 ± 6.9 mg/kg (range 6–29 mg/kg) (oral)

Sample size: 33