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Neuropharmacological Studies on Ibogaine, an Indole Alkaloid with Central-Stimulant Properties

Schneider, J. A., Sigg, E. B. · 1957 · Annals of the New York Academy of Sciences

Mechanisms Preclinical high

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Ibogaine produces EEG arousal via ascending reticular formation; effect blocked by atropine implicating cholinergic mechanism; paradoxical anticonvulsant properties despite central stimulation

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