Anti-addiction Drug Ibogaine Prolongs the Action Potential in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Safety (cardiac & more) In vitro high
AI-extracted · unverified · confirm at source
First proof ibogaine/noribogaine prolong action potential in human cardiomyocytes (hiPS-CM). Therapeutic concentrations retard repolarisation. Noribogaine's long half-life explains delayed cardiac events days after ingestion.
Dosing: 3µM test concentration (therapeutic range) (not-applicable)
Safety data present: HERG