Radioligand-binding study of noribogaine, a likely metabolite of ibogaine

Pearl, Sandra M., Herrick-Davis, Katherine, Teitler, Milton, Glick, Stanley D. · 1995 · Brain Research

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Noribogaine shows 3-4× higher affinity than ibogaine at κ (Kᵢ=0.96 μM vs 3.77 μM) and μ (Kᵢ=2.66 μM vs 11.04 μM) opioid receptors, and unlike ibogaine binds δ receptors (Kᵢ=24.72 μM)