Noribogaine stimulates naloxone-sensitive [³⁵S]GTPγS binding
Mechanisms In vitro high
AI-extracted · unverified · confirm at source
Noribogaine is a full μ-opioid agonist (EC₅₀ 324 nM, 170% maximal stimulation) comparable to DAMGO and morphine; ibogaine has negligible intrinsic activity. Identical G-protein population activated.