The Effects of Ibogaine on Uterine Smooth Muscle Contractions: Relation to the Activity of Antioxidant Enzymes
Mechanisms In vitro low
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Low ibogaine concentrations stimulate uterine contractions; higher doses inhibit. Concentration-dependent effects linked to ATP depletion and altered redox homeostasis. SOD1/GSH-Px/CAT activity changes.
Dosing: 1–60 mg/l ibogaine (isolated uterine tissue, cumulative dosing) (not-specified)