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The Effects of Ibogaine on Uterine Smooth Muscle Contractions: Relation to the Activity of Antioxidant Enzymes

Oreščanin-Dušić, Zorana, Tatalović, Nikola, Vidonja-Uzelac, Teodora, Nestorov, Jelena, Nikolić-Kokić, Aleksandra, Mijušković, Ana, Spasić, Mihajlo, Paškulin, Roman, Bresjanac, Mara, Blagojević, Duško · 2018 · Oxidative Medicine and Cellular Longevity

Mechanisms In vitro low

AI-extracted · unverified · confirm at source

Low ibogaine concentrations stimulate uterine contractions; higher doses inhibit. Concentration-dependent effects linked to ATP depletion and altered redox homeostasis. SOD1/GSH-Px/CAT activity changes.

Dosing: 1–60 mg/l ibogaine (isolated uterine tissue, cumulative dosing) (not-specified)

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