Main targets of ibogaine and noribogaine associated with its putative anti-addictive effects: A mechanistic overview

Oña, Genís, Reverte, Ingrid, Rossi, Giordano N., dos Santos, Rafael G., Hallak, Jaime E. C., Colomina, Maria Teresa, Bouso, José Carlos · 2023 · Journal of Psychopharmacology

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Updates Popik 1995 review. IBO/NOR modulate ≥8 targets (MOR, KOR, DAT, SERT, NMDA, nAChR α3β4, NTFs, ABC transporters). Advocates polypharmacology paradigm.