Ex vivo effects of ibogaine on the activity of antioxidative enzymes in human erythrocytes

Nikolić-Kokić, Aleksandra, Oreščanin-Dušić, Zorana, Spasojević, Ivan, Slavić, Marija, Mijušković, Ana, Paškulin, Roman, Miljević, Čedo, Spasić, Mihajlo B., Blagojević, Duško P. · 2015 · Journal of Ethnopharmacology

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Ex vivo ibogaine (10-20μM) elevates SOD1 and GR in human erythrocytes, increases plasma ATP dose-dependently, stabilises SOD1 against H₂O₂ — pro-antioxidant via energy metabolism.

Dosing: 10–20 µM ibogaine HCl (human erythrocytes ex vivo) (not-applicable)

Sample size: 13