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Ibogaine's potential role in supporting reward system recovery across diagnostic boundaries

Nicolas, Mark · 2025 · Frontiers in Pharmacology

Mechanisms Review moderate

AI-extracted · unverified · confirm at source

Transdiagnostic hypothesis: ibogaine restores reward system via GDNF, neuroplasticity, and DMN modulation. Proposes unified mechanism across OUD, depression, PTSD, TBI.

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