Psychedelics reopen the social reward learning critical period

Nardou, Romain, Sawyer, Edward, Song, Young Jun, Wilkinson, Makenzie, Padovan-Hernandez, Yasmin, de Deus, Júnia Lara, Wright, Noelle, Lama, Carine, Faltin, Sehr, Goff, Loyal A., Stein-O'Brien, Genevieve L., Dölen, Gül · 2023 · Nature

AI-extracted · unverified · confirm at source

All psychedelics reopen social reward learning critical period in mice; ibogaine open state ≥4 weeks (longest tested), proportional to 36-72h human subjective effects; convergent mechanism is ECM remodelling, not 5-HT₂A