Fatal Case of a 27-Year-Old Male After Taking Iboga in Withdrawal Treatment: GC-MS/MS Determination of Ibogaine and Ibogamine in Iboga Roots and Postmortem Biological Material

Mazoyer, Cédric, Carlier, Jérémy, Boucher, Alexandra, Péoc'h, Michel, Lemeur, Catherine, Gaillard, Yvan · 2013 · Journal of Forensic Sciences

AI-extracted · unverified · confirm at source

FATALITY CASE: 27yo male died ~12h after iboga root ingestion during withdrawal treatment. Femoral blood ibogaine 1.27 μg/mL. Co-ingestion with methadone and diazepam — triple QT-prolongation risk.

Dosing: Unknown; claimed 'teaspoon' (~108–144 mg ibogaine from 1.5–2g powder at 7.2%), but blood levels suggest substantially higher dose (possibly >20g powder) (oral)

Sample size: 1

Contraindications: Concurrent methadone use (dual QT-prolongation risk), Concurrent benzodiazepine use (potentiates methadone cardiotoxicity), Unsupervised treatment setting without medical monitoring, Unknown or unverified dose of crude iboga root bark, Polysubstance addiction history (15 years)