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Mania following use of ibogaine: A case series

Marta, Cole J., Ryan, Wesley C., Kopelowicz, Alex, Koek, Ralph J. · 2015 · American Journal on Addictions

Safety (cardiac & more) Case series high

AI-extracted · unverified · confirm at source

SAFETY ALERT: 3 cases de novo mania post-ibogaine, no prior bipolar history. Onset days-to-weeks post-use. Stimulant-induced mania excluded by tox; opiate withdrawal dismissed via Mr. C's opiate-naive history. First published mania reports.

Dosing: Unknown in all three cases (unregulated settings; doses not reported or verified) (oral)

Sample size: 3

Contraindications: Personal or family history of bipolar disorder or mania, Prior manic or psychotic episodes, Concurrent or recent psilocybin use (confounding psychiatric risk), Unregulated treatment setting without psychiatric monitoring or follow-up

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