The Iboga Alkaloids

Lavaud, Catherine, Massiot, Georges · 2017 · Progress in the Chemistry of Organic Natural Products

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117 new iboga alkaloids (2000–2016) from 14 species; ibogaine is weak MOR antagonist not agonist; 18-MC selectively targets α3β4 nAChR with no SERT/NMDA affinity; no scalable ibogaine synthesis exists