Distribution of Ibogaine and Noribogaine in a Man Following a Poisoning Involving Root Bark of the Tabernanthe iboga Shrub

Kontrimavičiūtė, Violeta, Mathieu, Olivier, Mathieu-Daudé, Jean-Claude, Vainauskas, Paulius, Casper, Thierry, Baccino, Eric, Bressolle, Françoise M.M. · 2006 · Journal of Analytical Toxicology

AI-extracted · unverified · confirm at source

First human tissue distribution of ibogaine/noribogaine post-mortem. Highest concentrations in lung (50.1/55.9 µg/g), liver (40.5/50.5 µg/g), brain (12.5/18.7 µg/g). Blood levels 5–20× therapeutic range.

Dosing: unknown (root bark, ~18 spoonfuls over ~10 hours, blood levels 5–20× therapeutic) (oral)

Sample size: 1

Contraindications: Unsupervised root bark ingestion, Concomitant drug abuse history, Absence of medical monitoring