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A Case of QT Prolongation and Torsades de Pointes Caused by Ibogaine Toxicity

Hildyard, Catherine, Macklin, Philip, Prendergast, Bernard, Bashir, Yaver · 2015 · The Journal of Emergency Medicine

Safety (cardiac & more) Case report high

AI-extracted · unverified · confirm at source

39yo male: QT 640→730ms (day 2)→400ms (day 7) after 7g oral ibogaine; no QTc correction formula specified. 8 episodes polymorphic VT/TdP, normal electrolytes. Suppressed by IV Mg 2g + transvenous overdrive pacing at 80bpm.

Dosing: 7 g oral (single dose, internet-sourced) (oral)

Sample size: 1

Safety data present: QTC, ELECTROLYTE

Contraindications: Pre-existing QT prolongation, Concurrent use of QT-prolonging drugs, History of seizures

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