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Tabernanthalog Reduces Motivation for Heroin and Alcohol in a Polydrug Use Model

Heinsbroek, Jasper A., Giannotti, Giuseppe, Bonilla, Joel, Olson, David E., Peters, Jamie · 2024 · Psychedelic Medicine

Mechanisms Preclinical moderate

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Tabernanthalog (TBG, 30mg/kg) efficacy in polydrug heroin+alcohol model. TBG reduced break points for both heroin (p=0.040) and alcohol (p=0.001). Non-hallucinogenic iboga analogue shows promise.

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