Mechanisms of Action of Ibogaine: Relevance to Putative Therapeutic Effects and Development of a Safer Iboga Alkaloid Congener

Glick, Stanley D., Maisonneuve, Isabelle M., Szumlinski, Karen K. · 2001 · The Alkaloids: Chemistry and Biology

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Comprehensive receptor screen of ibogaine, noribogaine, and 18-MC across 23 binding sites; 18-MC mimics antiaddictive efficacy without tremor, cerebellar toxicity, or cardiac effects; both reverse sensitised dopamine responses.