(±)-18-Methoxycoronaridine: A Novel Iboga Alkaloid Congener Having Potential Anti-Addictive Efficacy

Glick, Stanley D., Maisonneuve, Isabelle M., Hough, Lindsay B., Kuehne, Martin E., Bandarage, Upul K. · 1999 · CNS Drug Reviews

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DEFINITIVE 18-MC REVIEW: Synthesises preclinical evidence. Zero tremors/cerebellar toxicity at 100mg/kg (vs ibogaine Purkinje damage). Equivalent anti-addictive efficacy across morphine, cocaine, alcohol, nicotine.

Dosing: 20–40 mg/kg 18-MC (rat i.p./p.o.) (intraperitoneal)