Mechanisms of Antiaddictive Actions of Ibogaine

Glick, Stanley D., Maisonneuve, Isabelle M. · 1998 · Annals of the New York Academy of Sciences

AI-extracted · unverified · confirm at source

Ibogaine antiaddictive effects via κ-opioid + NMDA (opioids/stimulants), SERT (alcohol), nAChR antagonism (nicotine); σ₂ mediates neurotoxicity; 18-MC dissociates efficacy from toxicity.