Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum

Glick, Stanley D., Kuehne, Martin E., Raucci, Joseph, Wilson, Thomas E., Larson, David, Keller, Robert W. Jr., Carlson, J. Neil · 1994 · Brain Research

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R-enantiomers of ibogamine/coronaridine reduced morphine & cocaine self-admin without tremor; R-isomers decreased DA in NAC/STR while S-isomers had no effect. Anti-addictive and tremorigenic effects dissociable.