Effects of Ibogaine on Acute Signs of Morphine Withdrawal in Rats: Independence from Tremor

Glick, Stanley D., Rossman, Karen, Rao, N. C., Maisonneuve, Isabelle M., Carlson, J. Neil · 1992 · Neuropharmacology

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Ibogaine (40-80 mg/kg IP) significantly reduced 4 of 7 morphine withdrawal signs in rats; effects persisted 4 hr post-dose when tremors had fully dissipated, confirming independence from motor confounds.

Dosing: 20, 40 and 80 mg/kg IP (ibogaine HCl in saline, 1–4 ml/kg) (intraperitoneal)