Dimethyltryptamine (DMT) and ibogaine elicit membrane effects in HEK cells transiently transfected with the human 5-HT2A receptor
Mechanisms In vitro low
AI-extracted · unverified · confirm at source
Ibogaine (30-100μM) activates membrane currents in 5-HT2AR-transfected HEK cells via NSCC. I197V SNP shows shorter DMT response duration. First demonstration of 5-HT2AR-mediated ionic currents in this model.