Effects of ibogaine on responding maintained by food, cocaine and heroin reinforcement in rats

Dworkin, Steven I., Gleeson, Suzanne, Meloni, Domenico, Koves, Timothy R., Martin, Thomas J. · 1995 · Psychopharmacology

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Ibogaine (80 mg/kg IP) suppressed food, cocaine, and heroin self-administration in rats; heroin responding most sensitive. Effects not drug-specific — motor impairment may contribute.

Dosing: 40 and 80 mg/kg IP (ibogaine in water, 10 mg/ml) (intraperitoneal)