The Ibogaine Story — Chapter 7: Stanley Glick

De Rienzo, Paul, Beal, Dana · 1995

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First dose-response data: 5mg/kg gives 40% morphine reduction, 40mg gives 90%. After-effect persisted weeks. Transient kappa-opioid binding. Long-lasting metabolite hypothesis prefigures noribogaine.

Dosing: 2.5–80 mg/kg IP ibogaine in rats; 5–40 mg/kg IP dose-response on morphine self-administration; 40–80 mg/kg IP for persistent after-effect (intraperitoneal)