Unique and potent effects of acute ibogaine on zebrafish: The developing utility of novel aquatic models for hallucinogenic drug research

Cachat, Jonathan, Kyzar, Evan J., Collins, Christopher, Gaikwad, Siddharth, Green, Jeremy, Roth, Andrew, El-Ounsi, Mohamed, Davis, Ari, Pham, Mimi, Landsman, Samuel, Stewart, Adam Michael, Kalueff, Allan V. · 2013 · Behavioural Brain Research

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Zebrafish ibogaine exposure (10–20 mg/L) reverses geotaxis and scototaxis, disrupts shoaling, evokes melanophore darkening, and validates aquatic 3D phenotyping for hallucinogen research.

Dosing: 10–20 mg/L aquatic immersion (20 min pre-treatment)