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A transcriptomic analysis in mice following a single dose of ibogaine identifies new potential therapeutic targets

Biosca-Brull, Judit, Oña, Genís, Alarcón-Franco, Lineth, Colomina, Maria Teresa · 2024 · Translational Psychiatry

Mechanisms Preclinical high

AI-extracted · unverified · confirm at source

First transcriptomic analysis of ibogaine effects on gene expression in mouse frontal cortex (4h post-dose, 60mg/kg oral). Upregulated: hormonal pathways (Oxt, Avp), synaptogenesis genes.

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