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Fatalities Temporally Associated with the Ingestion of Ibogaine

Alper, Kenneth R., Stajić, Marina, Gill, James R. · 2012 · Journal of Forensic Sciences

Safety (cardiac & more) Syst. review landmark
⚠ Contains fatality data

AI-extracted · unverified · confirm at source

FOUNDATIONAL: Systematic review of all 19 ibogaine fatalities (1990-2008). 12/14 adequate autopsies showed cardiovascular comorbidities + polysubstance intoxication explained deaths. No characteristic neurotoxicity syndrome.

Dosing: 4.5–29 mg/kg (mean 14.3±6.1) (oral)

Sample size: 19

Contraindications: cardiovascular disease, coronary artery atherosclerosis, dilated cardiomyopathy, ventricular hypertrophy, liver disease, opioid co-use, benzodiazepine withdrawal, alcohol withdrawal, cocaine use, hypokalemia, hypomagnesemia

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