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Ibogaine and the inhibition of acetylcholinesterase

Alper, Kenneth R., Reith, Maarten E. A., Sershen, Henry · 2011 · Journal of Ethnopharmacology

Mechanisms In vitro low

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NOVEL MECHANISM: Ibogaine inhibits acetylcholinesterase, contributing to muscarinic cholinergic effects. Adds to multi-receptor profile and may explain some pharmacological/toxicological properties.

Dosing: N/A (IC₅₀ = 520 ± 40 µM for AChE inhibition) (not-specified)

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