Old Dog, New Tricks: Ibogaine and Its Analogs as Potential Neurotherapeutics
Mechanisms Review high
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Comprehensive review of ibogaine pharmacology and synthetic analogues. 18-MC and tabernanthalog show therapeutic potential without cardiotoxicity (hERG IC₅₀ >50μM and 148μM respectively). Texas allocated $50M for ibogaine clinical research.
Safety data present: HERG